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12-2014 | Withdrawal of antiepileptic drugs

A currently 57-year-old female patient suffered first generalized tonic clonic epileptic seizures from wakefulness in her 26th year of life. Partial onset of seizures was not reported. Multiple EEGs and neuroimaging (CT and MRI scans) were normal, the cause of epilepsy remained unclear. In summary, this patient suffers from undetermined epilepsy as the available information […]

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11-2014 | Is one seizure epilepsy?

A 22-year old male patient suffers a first tonic-clonic generalized epileptic seizure. The seizure occurs from wakefulness at midday. Focal onset of this seizure is not reported. In the night before the seizure, sleep duration was shorter than usual. Other clinical seizure forms so far had not occurred. In routine EEG, generalized spike-wave-discharges at 3 […]

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10-2014 | Two antiepileptics better than three

A 42-year old patient with moderately severe mental retardation suffers from partial epilepsy since early childhood. He can not express if his has any auras, but previously frequent automotor (= complex partial) and generalized tonic-clonic (= Grand Mal) seizures occurred. The current antiepileptic treatment regimen comprises phenytoin 350 mg, levetiracetam 2,000 mg and lacosamide 400 […]

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9-2014 | Falls with laughter

The 27-year-old female patient presents in the outpatient clinic because she abruptly loses muscle strength when she has to laugh or when she trains intensely at the gym. The muscles of the neck are mostly involved, but her muscles in her arms and legs can also be affected so that objects can fall out of […]

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8-2014 | Seizure freedom of top priority

A 22-year-old female patient for the first time presents in our epilepsy outpatient department. Since the age of 16 years, she suffers from regularly occurring seizures that are characterized by loss of contact and non-reagibility as well as prominent oral and manual automatisms. From a semiological point of view, these are typical automotor (= complex […]

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7-2014 | Seizure reduction with ketogenic diet

A 7-year-old girl suffers since her 3rd year of life from daily episodes with impaired consciousness, these are accompanied by discrete oral automatisms. Duration of these presumably atypical absence seizures is 15-20 sec. The child additionally suffers from a moderate global developmental disorder, she attends a school for children with special needs. The cause for […]

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6-2014 | Seizure free 1 year post surgery

An 18-year-old man suffers from partial epilepsy since early school years. Epilepsy is characterized by 2-3 automotor (= complex partial) seizures per month. In the past years, the patient was treated with four different antiepileptic drugs, however without any significant impact on seizure frequency. His epilepsy was caused by left-sided hippocampal sclerosis, i.e. a scar […]

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5-2014 | Adolescent with arm jerks

A 16-year-old young man reported almost daily jerks in his arms, that first have occurred 6 months ago. He further said that these sudden lancinating movements originate in his shoulders. These jerks manifest almost always in the early morning in the first 60 min. after awakening. Epileptic seizures with loss or impairment of consciousness were […]

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4-2014 | No antiepileptics despite seizures

A 28-year old patient suffers from epilepsy with Grand Mal for 5 years. Seizures manifest while awake, but without any further binding to the sleep-wake-cycle. Even purposeful asking did not give hints for focal onset of seizure semiology. Routine and sleep-deprivation EEG were normal as was cerebral MRI. We allocated the condition to unclassified epilepsy, […]

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3-2014 | Psychogenic non-epileptic seizures

A 35-year-old female patient suffers from seizures for 10 years. Her disorder commenced during a grievous separation. Seizures are characterized by twitching and beating of all extremities and prominent movements of her trunk and pelvis. These seizures have been diagnosed epileptic 10 years ago. Since then, the patient has regularly taken antiepileptic drugs (at first […]

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2-2014 | Refusal of indication for epilepsy surgery

A 43-year-old female patient suffers from partial epilepsy with automotor (= complex partial) seizures for 25 years (seizure frequency, 4-5 per month). Seizures are characterized by impaired consciousness and oral automatisms. Seizures are preceded by epigastric auras. In the past years, the patient was administered eight different antiepileptic drugs that eventually failed to control her […]

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1-2014 | Awakening with tapering of antiepileptics

A 39-year old female patient with childhood onset epilepsy was admitted to the Epilepsy-Center Berlin-Brandenburg due to intense tiredness, desorientation und impaired speech production. The patient suffers from learning disability, she lives in assisted accommodation. She has partial epilepsy, automotor (= complex partial) seizures with impaired consciousness and oral automatisms are reported to manifest every […]

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